1. OverviewΒΆ

This tutorial focuses on several of the basic use cases for VarSeq and its integration with a VSWarehouse server. The VSWarehouse server allows for the simple centralized management of the variants and samples previously imported in VarSeq. Using VSWarehouse as part of an existing VarSeq workflow allows users to add previously seen variants to the current project. This can include variants from previous projects, reports or assessment catalogs. These resource are all centrally located allowing for easy management and collaboration.

The typical VarSeq workflow with VSWarehouse can be summarized with the following .

  • The variants are imported in VarSeq where they are filtered down to the ones which are relevant.
  • Annotation sources from VSWarehouse are added to autofill previous variants or assessments in order to speed up the final interpretation step.
  • Once the initial variants have been reduced down to an actionable result set, they can be included in a report that is rendered and stored on the VSWarehouse.
  • Additionally variant specific notes can be added to a VSWarehouse assessment catalog.
  • Finally once the reporting is finished the project is uploaded to the VSWarehouse where its variants are added to a cohort of samples that underwent similar analysis.

The VarSeq project that is included in the ZIP file that accompanies this tutorial can be used to walk through this tutorial. Alternatively if you have previously completed the Cancer Panel VarSeq tutorial you can use that project to complete this tutorial.