3.10.5. Mendel Error¶
This algorithm computes the Mendel Error status for the child’s genotype. The status is categorized as follows:
Untransmitted: The allele was not inherited by the child.
Transmitted: The allele was inherited by the child
de Novo Allele: The child’s genotype shows a single de Novo mutation that was not present in either parent.
MIE: Mendel Inheritance Error. The child’s genotype cannot be explained by mendelian inheritance patterns and is more complex than a single de Novo mutation.
Missing alleles are considered to be reference.
Requires a genotype (GT) sample level field.
Requires that the sample have at least one parent
Creates a categorical column on each child sample denoting its Mendel Error status